教师的研究

教授essor Granados-Focil’s research focuses on better understanding the principles controlling charge transport within polymeric matrices and establishing a roadmap towards nano-structured, multifunctional materials with improved ionic conductivity or optoelectronic properties. 可再生能源替代品, flexible optoelectronic devices and better energy storage are promising areas that will benefit from tailoring the materials properties via a precise control of their structure at the molecular and supramolecular scales.

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研究实验室

教授essor 双红霍’s research focuses on on computer simulation of molecular interactions in complex systems, particularly protein-protein interactions and protein-small molecule interactions; computer-aided, structure-based drug design; and development of novel computational algorithms to study enzyme reaction mechanism.

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研究实验室

Jakobsche教授的研究包括：

• 利用合成有机化学来制造目标分子.
• Designing functional probe molecules that have well defined interactions with particular proteins or other biological structures and that can be used for chemical biology analysis of these systems.
• Developing new organic chemistry reactions that can help enable more efficient synthesis of target molecules.
• Performing detailed analysis of reactions or molecular structures to better understand the properties and reactivities of unusual organic molecules.
• Using chemistry to learn about biological systems that are relevant to diseases, 药物, 或者免疫系统.

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研究实验室

教授essor Lazo’s research is focused on the biophysics of misfolding and self-assembly of proteins associated with disease. Proteins of interest include the amyloid β-protein in Alzheimer’s disease, 胰岛淀粉样蛋白多肽与2型糖尿病相关, 各种形式的朊病毒中的朊蛋白, 以及与大疱性表皮松解症有关的皮肤蛋白质, a disease characterized by skin blistering following little or no trauma.

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研究实验室

教授essor Nag’s lab develops unique peptide or peptidomimetic macrocycles using robust chemical reactions and Solid Phase Peptide Synthesis. 重点, 分子量约为1,000, 在小分子和蛋白质之间架起桥梁, 在大小和组成方面. Chemical synthesis of macrocycles allows one to incorporate unique properties such as thermal and protease stability and inclusion of small molecules. 利用大环分子识别的力量, her lab is currently working on different aspects of biological chemistry and catalysis.

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研究实验室

教授essor Smith’s research examines the structures and dynamics of materials in which organization of complex compositions over small length scales occurs: high surface area layered, 剥落了, or mesoporous metal oxides and inorganic/organic nanocomposites.

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教授essor Spratt’s research is focused on the regulation of enzyme catalysis and protein function. Interactions between two or more proteins plays an integral role in cell division and homeostasis. The development of various human diseases can occur when these protein-protein interactions are disrupted or modified. Understanding how these protein-protein interactions affect an enzyme’s ability to make or break bonds and its underlying mechanism is an important step in drug design/development.

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研究实验室

教授essor Turnbull’s research lies in the preparation of new materials, focusing on two areas:

• 分子磁性, 利用我们对结构的理解, bonding and geometry to control the bulk magnetic properties of a material at the molecular level.
• Low-dimensional Antiferromagnets: Copper oxide-based high temperature superconductors introduced a new era to the field of conducting materials, but the mechanism of their superconductivity is still not well understood.

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